| อันดับ | เมือง | รัฐ | จำนวนประชากร |
| 1 | New York | New York | 8,398,748 |
| 2 | Los Angeles | California | 3,990,456 |
| 3 | Chicago | Illinois | 2,705,994 |
| 4 | Houston | Texas | 2,325,502 |
| 5 | Phoenix | Arizona | 1,660,272 |
| 6 | Philadelphia | Pennsylvania | 1,584,138 |
| 7 | San Antonio | Texas | 1,532,233 |
| 8 | San Diego | California | 1,425,976 |
| 9 | Dallas | Texas | 1,345,047 |
| 10 | San Jose | California | 1,030,119 |
| 11 | Austin | Texas | 964,254 |
| 12 | Jacksonville | Florida | 903,889 |
| 13 | Fort Worth | Texas | 895,008 |
| 14 | Columbus | Ohio | 892,533 |
| 15 | San Francisco | California | 883,305 |
| 16 | Charlotte | North Carolina | 872,498 |
| 17 | Indianapolis | Indiana | 867,125 |
| 18 | Seattle | Washington | 744,955 |
| 19 | Denver | Colorado | 716,492 |
| 20 | Washington | District of Columbia | 702,455 |
| 21 | Boston | Massachusetts | 694,583 |
| 22 | El Paso | Texas | 682,669 |
| 23 | Detroit | Michigan | 672,662 |
| 24 | Nashville | Tennessee | 669,053 |
| 25 | Portland | Oregon | 653,115 |
| 26 | Memphis | Tennessee | 650,618 |
| 27 | Oklahoma City | Oklahoma | 649,021 |
| 28 | Las Vegas | Nevada | 644,644 |
| 29 | Louisville | Kentucky | 620,118 |
| 30 | Baltimore | Maryland | 602,495 |
| 31 | Milwaukee | Wisconsin | 592,025 |
| 32 | Albuquerque | New Mexico | 560,218 |
| 33 | Tucson | Arizona | 545,975 |
| 34 | Fresno | California | 530,093 |
| 35 | Mesa | Arizona | 508,958 |
| 36 | Sacramento | California | 508,529 |
| 37 | Atlanta | Georgia | 498,044 |
| 38 | Kansas City | Missouri | 491,918 |
| 39 | Colorado Springs | Colorado | 472,688 |
| 40 | Miami | Florida | 470,914 |
| 41 | Raleigh | North Carolina | 469,298 |
| 42 | Omaha | Nebraska | 468,262 |
| 43 | Long Beach | California | 467,354 |
| 44 | Virginia Beach | Virginia | 450,189 |
| 45 | Oakland | California | 429,082 |
| 46 | Minneapolis | Minnesota | 425,403 |
| 47 | Tulsa | Oklahoma | 400,669 |
| 48 | Arlington | Texas | 398,112 |
| 49 | Tampa | Florida | 392,890 |
| 50 | New Orleans | Louisiana | 391,006 |
| 51 | Wichita | Kansas | 389,255 |
| 52 | Cleveland | Ohio | 383,793 |
| 53 | Bakersfield | California | 383,579 |
| 54 | Aurora | Colorado | 374,114 |
| 55 | Anaheim | California | 352,005 |
| 56 | Honolulu | Hawaii | 347,397 |
| 57 | Santa Ana | California | 332,725 |
| 58 | Riverside | California | 330,063 |
| 59 | Corpus Christi | Texas | 326,554 |
| 60 | Lexington | Kentucky | 323,780 |
| 61 | Stockton | California | 311,178 |
| 62 | Henderson | Nevada | 310,390 |
| 63 | Saint Paul | Minnesota | 307,695 |
| 64 | St. Louis | Missouri | 302,838 |
| 65 | Cincinnati | Ohio | 302,605 |
| 66 | Pittsburgh | Pennsylvania | 301,048 |
| 67 | Greensboro | North Carolina | 294,722 |
| 68 | Anchorage | Alaska | 291,538 |
| 69 | Plano | Texas | 288,061 |
| 70 | Lincoln | Nebraska | 287,401 |
| 71 | Orlando | Florida | 285,713 |
| 72 | Irvine | California | 282,572 |
| 73 | Newark | New Jersey | 282,090 |
| 74 | Toledo | Ohio | 274,975 |
| 75 | Durham | North Carolina | 274,291 |
| 76 | Chula Vista | California | 271,651 |
| 77 | Fort Wayne | Indiana | 267,633 |
| 78 | Jersey City | New Jersey | 265,549 |
| 79 | St. Petersburg | Florida | 265,098 |
| 80 | Laredo | Texas | 261,639 |
| 81 | Madison | Wisconsin | 258,054 |
| 82 | Chandler | Arizona | 257,165 |
| 83 | Buffalo | New York | 256,304 |
| 84 | Lubbock | Texas | 255,885 |
| 85 | Scottsdale | Arizona | 255,310 |
| 86 | Reno | Nevada | 250,998 |
| 87 | Glendale | Arizona | 250,702 |
| 88 | Gilbert | Arizona | 248,279 |
| 89 | Winston–Salem | North Carolina | 246,328 |
| 90 | North Las Vegas | Nevada | 245,949 |
| 91 | Norfolk | Virginia | 244,076 |
| 92 | Chesapeake | Virginia | 242,634 |
| 93 | Garland | Texas | 242,507 |
| 94 | Irving | Texas | 242,242 |
| 95 | Hialeah | Florida | 238,942 |
| 96 | Fremont | California | 237,807 |
| 97 | Boise | Idaho | 228,790 |
| 98 | Richmond | Virginia | 228,783 |
| 99 | Baton Rouge | Louisiana | 221,599 |
| 100 | Spokane | Washington | 219,190 |
ข้อมูลอ้างอิงจากปี 2018